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The Inhibition of microRNA-128 on IGF-1-Activating mTOR Signaling Involves in Temozolomide-Induced Glioma Cell Apoptotic Death

Temozolomide (TMZ), an alkylating agent of the imidazotetrazine series, is a first-line chemotherapeutic drug used in the clinical therapy of glioblastoma multiforme, the most common and high-grade primary glioma in adults. Micro (mi)RNAs, which are small noncoding RNAs, post-transcriptionally regul...

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Detalles Bibliográficos
Autores principales: Chen, Peng-Hsu, Cheng, Chia-Hsiung, Shih, Chwen-Ming, Ho, Kuo-Hao, Lin, Cheng-Wei, Lee, Chin-Cheng, Liu, Ann-Jeng, Chang, Cheng-Kuei, Chen, Ku-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125683/
https://www.ncbi.nlm.nih.gov/pubmed/27893811
http://dx.doi.org/10.1371/journal.pone.0167096

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