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The Inhibition of microRNA-128 on IGF-1-Activating mTOR Signaling Involves in Temozolomide-Induced Glioma Cell Apoptotic Death
Temozolomide (TMZ), an alkylating agent of the imidazotetrazine series, is a first-line chemotherapeutic drug used in the clinical therapy of glioblastoma multiforme, the most common and high-grade primary glioma in adults. Micro (mi)RNAs, which are small noncoding RNAs, post-transcriptionally regul...
Autores principales: | Chen, Peng-Hsu, Cheng, Chia-Hsiung, Shih, Chwen-Ming, Ho, Kuo-Hao, Lin, Cheng-Wei, Lee, Chin-Cheng, Liu, Ann-Jeng, Chang, Cheng-Kuei, Chen, Ku-Chung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125683/ https://www.ncbi.nlm.nih.gov/pubmed/27893811 http://dx.doi.org/10.1371/journal.pone.0167096 |
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