Azidothymidine Sensitizes Primary Effusion Lymphoma Cells to Kaposi Sarcoma-Associated Herpesvirus-Specific CD4+ T Cell Control and Inhibits vIRF3 Function

Kaposi sarcoma-associated herpesvirus (KSHV) is linked with the development of Kaposi sarcoma and the B lymphocyte disorders primary effusion lymphoma (PEL) and multi-centric Castleman disease. T cell immunity limits KSHV infection and disease, however the virus employs multiple mechanisms to inhibi...

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Detalles Bibliográficos
Autores principales: Williamson, Samantha J., Nicol, Samantha M., Stürzl, Michael, Sabbah, Shereen, Hislop, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125715/
https://www.ncbi.nlm.nih.gov/pubmed/27893813
http://dx.doi.org/10.1371/journal.ppat.1006042

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