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PBPK modeling and simulation in drug research and development

Physiologically based pharmacokinetic (PBPK) modeling and simulation can be used to predict the pharmacokinetic behavior of drugs in humans using preclinical data. It can also explore the effects of various physiologic parameters such as age, ethnicity, or disease status on human pharmacokinetics, a...

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Detalles Bibliográficos
Autores principales:	Zhuang, Xiaomei, Lu, Chuang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125732/ https://www.ncbi.nlm.nih.gov/pubmed/27909650 http://dx.doi.org/10.1016/j.apsb.2016.04.004

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