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Genetic and epigenetic heterogeneity of epithelial ovarian cancer and the clinical implications for molecular targeted therapy

Epithelial ovarian cancer (EOC) is the most lethal gynaecological malignancy, and tumoural heterogeneity (TH) has been blamed for treatment failure. The genomic and epigenomic atlas of EOC varies significantly with tumour histotype, grade, stage, sensitivity to chemotherapy and prognosis. Rapidly ac...

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Detalles Bibliográficos
Autores principales:	Bai, Huimin, Cao, Dongyan, Yang, Jiaxin, Li, Menghui, Zhang, Zhenyu, Shen, Keng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125785/ https://www.ncbi.nlm.nih.gov/pubmed/26800494 http://dx.doi.org/10.1111/jcmm.12771

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