Cargando…

Opposing Post-Translational Modifications Regulate Cep76 Function to Suppress Centriole Amplification

Centrioles are critical for many cellular processes including cell division and cilia assembly. The number of centrioles within a cell is under strict control, and deregulation of centriole copy number is a hallmark of cancer. The molecular mechanisms that halt centriole amplification have not been...

Descripción completa

Detalles Bibliográficos
Autores principales: Barbelanne, Marine, Chiu, Andrea, Qian, Jin, Tsang, William Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125818/
https://www.ncbi.nlm.nih.gov/pubmed/27065328
http://dx.doi.org/10.1038/onc.2016.74