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Opposing Post-Translational Modifications Regulate Cep76 Function to Suppress Centriole Amplification
Centrioles are critical for many cellular processes including cell division and cilia assembly. The number of centrioles within a cell is under strict control, and deregulation of centriole copy number is a hallmark of cancer. The molecular mechanisms that halt centriole amplification have not been...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125818/ https://www.ncbi.nlm.nih.gov/pubmed/27065328 http://dx.doi.org/10.1038/onc.2016.74 |