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STAT3 Potentiates SIAH-1 Mediated Proteasomal Degradation of β-Catenin in Human Embryonic Kidney Cells

The β-catenin functions as an adhesion molecule and a component of the Wnt signaling pathway. In the absence of the Wnt ligand, β-catenin is constantly phosphorylated, which designates it for degradation by the APC complex. This process is one of the key regulatory mechanisms of β-catenin. The level...

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Detalles Bibliográficos
Autores principales:	Shin, Minkyung, Yi, Eun Hee, Kim, Byung-Hak, Shin, Jae-Cheon, Park, Jung Youl, Cho, Chung-Hyun, Park, Jong-Wan, Choi, Kang-Yell, Ye, Sang-Kyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125938/ https://www.ncbi.nlm.nih.gov/pubmed/27871173 http://dx.doi.org/10.14348/molcells.2016.0212

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