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Four Years Prospective Study of Natural History of Atopic Dermatitis Aged 7~8 Years at an Individual Level: A Community-Based Survey by Dermatologists' Skin Examination in Childhood

BACKGROUND: The age-dependent change in atopic dermatitis (AD) at an individual level has mostly performed in a hospital-setting. OBJECTIVE: We evaluated the age-dependent change of AD symptoms at an individual level in a community-setting. METHODS: For the diagnostic accuracy, all participants of s...

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Autores principales: Kim, Young Jee, Yun, Sook Jung, Lee, Jee-Bum, Kim, Seong Jin, Won, Young Ho, Lee, Seung-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Dermatological Association; The Korean Society for Investigative Dermatology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125948/
https://www.ncbi.nlm.nih.gov/pubmed/27904266
http://dx.doi.org/10.5021/ad.2016.28.6.684
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author Kim, Young Jee
Yun, Sook Jung
Lee, Jee-Bum
Kim, Seong Jin
Won, Young Ho
Lee, Seung-Chul
author_facet Kim, Young Jee
Yun, Sook Jung
Lee, Jee-Bum
Kim, Seong Jin
Won, Young Ho
Lee, Seung-Chul
author_sort Kim, Young Jee
collection PubMed
description BACKGROUND: The age-dependent change in atopic dermatitis (AD) at an individual level has mostly performed in a hospital-setting. OBJECTIVE: We evaluated the age-dependent change of AD symptoms at an individual level in a community-setting. METHODS: For the diagnostic accuracy, all participants of schoolchildren were received skin examination by dermatologists (twice a year for the same group), instead of questionnaire-based surveys. For this study, sequential check-ups of 273 elementary school children, aged 7~8 years, were performed for 4 years up to the age of 10~11 years. RESULTS: Among the 47 AD children, who had been diagnosed as having AD at the first-year check-up, spontaneous remission was detected in nine children during the follow-up periods (remission rate of 19.1%). As a consequence, the one-year AD prevalence was decreased by 5.9% in the elementary schoolchildren over four years. Unexpectedly, late onset (after 8 years of age) AD was observed in 21.7% of AD children. There was no statistically significant relationship between spontaneous remission and host factors including sex and family history of atopic diseases. CONCLUSION: We observed that 19.1% of AD children in the age group of 7~11 years showed spontaneous remission based on skin examination by dermatologists. There might be an increase in the prevalence of late onset AD in Korea.
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spelling pubmed-51259482016-12-01 Four Years Prospective Study of Natural History of Atopic Dermatitis Aged 7~8 Years at an Individual Level: A Community-Based Survey by Dermatologists' Skin Examination in Childhood Kim, Young Jee Yun, Sook Jung Lee, Jee-Bum Kim, Seong Jin Won, Young Ho Lee, Seung-Chul Ann Dermatol Original Article BACKGROUND: The age-dependent change in atopic dermatitis (AD) at an individual level has mostly performed in a hospital-setting. OBJECTIVE: We evaluated the age-dependent change of AD symptoms at an individual level in a community-setting. METHODS: For the diagnostic accuracy, all participants of schoolchildren were received skin examination by dermatologists (twice a year for the same group), instead of questionnaire-based surveys. For this study, sequential check-ups of 273 elementary school children, aged 7~8 years, were performed for 4 years up to the age of 10~11 years. RESULTS: Among the 47 AD children, who had been diagnosed as having AD at the first-year check-up, spontaneous remission was detected in nine children during the follow-up periods (remission rate of 19.1%). As a consequence, the one-year AD prevalence was decreased by 5.9% in the elementary schoolchildren over four years. Unexpectedly, late onset (after 8 years of age) AD was observed in 21.7% of AD children. There was no statistically significant relationship between spontaneous remission and host factors including sex and family history of atopic diseases. CONCLUSION: We observed that 19.1% of AD children in the age group of 7~11 years showed spontaneous remission based on skin examination by dermatologists. There might be an increase in the prevalence of late onset AD in Korea. Korean Dermatological Association; The Korean Society for Investigative Dermatology 2016-12 2016-11-23 /pmc/articles/PMC5125948/ /pubmed/27904266 http://dx.doi.org/10.5021/ad.2016.28.6.684 Text en Copyright © 2016 The Korean Dermatological Association and The Korean Society for Investigative Dermatology http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kim, Young Jee
Yun, Sook Jung
Lee, Jee-Bum
Kim, Seong Jin
Won, Young Ho
Lee, Seung-Chul
Four Years Prospective Study of Natural History of Atopic Dermatitis Aged 7~8 Years at an Individual Level: A Community-Based Survey by Dermatologists' Skin Examination in Childhood
title Four Years Prospective Study of Natural History of Atopic Dermatitis Aged 7~8 Years at an Individual Level: A Community-Based Survey by Dermatologists' Skin Examination in Childhood
title_full Four Years Prospective Study of Natural History of Atopic Dermatitis Aged 7~8 Years at an Individual Level: A Community-Based Survey by Dermatologists' Skin Examination in Childhood
title_fullStr Four Years Prospective Study of Natural History of Atopic Dermatitis Aged 7~8 Years at an Individual Level: A Community-Based Survey by Dermatologists' Skin Examination in Childhood
title_full_unstemmed Four Years Prospective Study of Natural History of Atopic Dermatitis Aged 7~8 Years at an Individual Level: A Community-Based Survey by Dermatologists' Skin Examination in Childhood
title_short Four Years Prospective Study of Natural History of Atopic Dermatitis Aged 7~8 Years at an Individual Level: A Community-Based Survey by Dermatologists' Skin Examination in Childhood
title_sort four years prospective study of natural history of atopic dermatitis aged 7~8 years at an individual level: a community-based survey by dermatologists' skin examination in childhood
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125948/
https://www.ncbi.nlm.nih.gov/pubmed/27904266
http://dx.doi.org/10.5021/ad.2016.28.6.684
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