Cargando…

Effect of inserted spacer in hepatic cell-penetrating multifunctional peptide component on the DNA intracellular delivery of quaternary complexes based on modular design

A safe and efficient quaternary gene delivery system (named Q-complexes) was constructed based on self-assembly of molecules through noncovalent bonds. This system was formulated through the cooperation and competing interactions of cationic liposomes, multifunctional peptides, and DNA, followed by...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Luchen, Li, Zhenbo, Sun, Fangli, Xu, Yuhong, Du, Zixiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126006/
https://www.ncbi.nlm.nih.gov/pubmed/27920533
http://dx.doi.org/10.2147/IJN.S115381