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Effect of inserted spacer in hepatic cell-penetrating multifunctional peptide component on the DNA intracellular delivery of quaternary complexes based on modular design
A safe and efficient quaternary gene delivery system (named Q-complexes) was constructed based on self-assembly of molecules through noncovalent bonds. This system was formulated through the cooperation and competing interactions of cationic liposomes, multifunctional peptides, and DNA, followed by...
Autores principales: | Zhang, Luchen, Li, Zhenbo, Sun, Fangli, Xu, Yuhong, Du, Zixiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126006/ https://www.ncbi.nlm.nih.gov/pubmed/27920533 http://dx.doi.org/10.2147/IJN.S115381 |
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