Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning

The mammalian kidney contains nephrons comprising glomeruli and tubules joined to ureteric bud–derived collecting ducts. It has a characteristic bean-like shape, with near-complete rostrocaudal symmetry around the hilum. Here we show that Celsr1, a planar cell polarity (PCP) gene implicated in neura...

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Detalles Bibliográficos
Autores principales: Brzóska, Hortensja Ł., d’Esposito, Angela M., Kolatsi-Joannou, Maria, Patel, Vishal, Igarashi, Peter, Lei, Yunping, Finnell, Richard H., Lythgoe, Mark F., Woolf, Adrian S., Papakrivopoulou, Eugenia, Long, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126096/
https://www.ncbi.nlm.nih.gov/pubmed/27597235
http://dx.doi.org/10.1016/j.kint.2016.07.011

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