Cargando…

Activated IL-1RI Signaling Pathway Induces Th17 Cell Differentiation via Interferon Regulatory Factor 4 Signaling in Patients with Relapsing-Remitting Multiple Sclerosis

IL-1β plays a crucial role in the differentiation of human Th17 cells. We report here that IL-1RI expression is significantly increased in both naive and memory CD4(+) T cells derived from relapsing-remitting multiple sclerosis (RR MS) patients in comparison to healthy controls. Interleukin 1 recept...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sha, Yonggang, Markovic-Plese, Silva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126112/ https://www.ncbi.nlm.nih.gov/pubmed/27965670 http://dx.doi.org/10.3389/fimmu.2016.00543

Ejemplares similares

Immune Regulatory Cell Bias Following Alemtuzumab Treatment in Relapsing-Remitting Multiple Sclerosis
por: Kashani, Nicole, et al.
Publicado: (2021)

Natural Killer Cells Regulate Th17 Cells After Autologous Hematopoietic Stem Cell Transplantation for Relapsing Remitting Multiple Sclerosis
por: Darlington, Peter J., et al.
Publicado: (2018)

Profiling of Canonical and Non-Traditional Cytokine Levels in Interferon-β-Treated Relapsing–Remitting-Multiple Sclerosis Patients
por: D’Angelo, Chiara, et al.
Publicado: (2018)

Cytotoxic B Cells in Relapsing-Remitting Multiple Sclerosis Patients
por: Boldrini, Vinícius O., et al.
Publicado: (2022)

Coagulation/Complement Activation and Cerebral Hypoperfusion in Relapsing-Remitting Multiple Sclerosis
por: Koudriavtseva, Tatiana, et al.
Publicado: (2020)

Immunological Subsets Characterization in Newly Diagnosed Relapsing–Remitting Multiple Sclerosis
por: D’Amico, Emanuele, et al.
Publicado: (2022)

IL-11 in multiple sclerosis
por: Zhang, Xin, et al.
Publicado: (2015)

Low Memory T Cells Blood Counts and High Naïve Regulatory T Cells Percentage at Relapsing Remitting Multiple Sclerosis Diagnosis
por: Canto-Gomes, João, et al.
Publicado: (2022)

Profile of PEGylated interferon beta in the treatment of relapsing-remitting multiple sclerosis
por: Cocco, Eleonora, et al.
Publicado: (2015)

The innovative development in interferon beta treatments of relapsing‐remitting multiple sclerosis
por: Madsen, Claus
Publicado: (2017)

Expansion of Neutrophils and Classical and Nonclassical Monocytes as a Hallmark in Relapsing-Remitting Multiple Sclerosis
por: Haschka, David, et al.
Publicado: (2020)

Tissue factor as a potential coagulative/vascular marker in relapsing-remitting multiple sclerosis
por: Koudriavtseva, Tatiana, et al.
Publicado: (2023)

Regulation of Suppressors of Cytokine Signaling as a Therapeutic Approach in Autoimmune Diseases, with an Emphasis on Multiple Sclerosis
por: Ramgolam, Vinod S., et al.
Publicado: (2011)

Approved Beta Interferons in Relapsing-Remitting Multiple Sclerosis: Is There an Odd One Out?
por: Clapin, Alexis
Publicado: (2012)

The Assessment for Disinvestment of Intramuscular Interferon Beta for Relapsing-Remitting Multiple Sclerosis in Brazil
por: Lemos, Livia Lovato Pires de, et al.
Publicado: (2017)

Identification and Clinical Validation of Key Extracellular Proteins as the Potential Biomarkers in Relapsing-Remitting Multiple Sclerosis
por: Li, Meng, et al.
Publicado: (2021)

An Interaction Library for the FcεRI Signaling Network
por: Chylek, Lily A., et al.
Publicado: (2014)

Regulation of Interferon Gamma Signaling by Suppressors of Cytokine Signaling and Regulatory T Cells
por: Larkin, Joseph, et al.
Publicado: (2013)

Effect of Treatment with Interferon Beta-1a on Changes in Voxel-Wise Magnetization Transfer Ratio in Normal Appearing Brain Tissue and Lesions of Patients with Relapsing–Remitting Multiple Sclerosis: A 24-Week, Controlled Pilot Study
por: Zivadinov, Robert, et al.
Publicado: (2014)

IL-1-IL-17 Signaling Axis Contributes to Fibrosis and Inflammation in Two Different Murine Models of Systemic Sclerosis
por: Park, Min-Jung, et al.
Publicado: (2018)

Commentary: Acute Hemorrhagic Leukoencephalitis (Weston–Hurst Syndrome) in a Patient with Relapse-Remitting Multiple Sclerosis
por: Koudriavtseva, Tatiana
Publicado: (2016)

Increased intrathecal neurofilament light and immunoglobulin M predict severe disability in relapsing-remitting multiple sclerosis
por: Rosenstein, Igal, et al.
Publicado: (2022)

Contribution of IL-1RI Signaling to Protection against Cryptococcus neoformans 52D in a Mouse Model of Infection
por: Shourian, Mitra, et al.
Publicado: (2018)

TRAF Regulation of IL-17 Cytokine Signaling
por: Swaidani, Shadi, et al.
Publicado: (2019)

ERα Signaling Increased IL-17A Production in Th17 Cells by Upregulating IL-23R Expression, Mitochondrial Respiration, and Proliferation
por: Fuseini, Hubaida, et al.
Publicado: (2019)

Erratum: Regulation of Interferon Gamma Signaling by Suppressors of Cytokine Signaling and Regulatory T Cells
por: Larkin, Joseph, et al.
Publicado: (2014)

High levels of kappa free light chain synthesis predict cognitive decline in relapsing-remitting multiple sclerosis
por: Rosenstein, Igal, et al.
Publicado: (2023)

Regulatory effects of C5a on IL-17A, IL-17F, and IL-23
por: Grailer, Jamison J., et al.
Publicado: (2013)

Disturbed T Cell Signaling and Altered Th17 and Regulatory T Cell Subsets in the Pathogenesis of Systemic Lupus Erythematosus
por: Rother, Nils, et al.
Publicado: (2015)

Monitoring interferon β treatment response with magnetic resonance spectroscopy in relapsing remitting multiple sclerosis
por: Yetkin, Mehmet Fatih, et al.
Publicado: (2016)

Advances in the treatment of relapsing–remitting multiple sclerosis: the role of pegylated interferon β-1a
por: Furber, Kendra L, et al.
Publicado: (2017)

B-Cell Activity Predicts Response to Glatiramer Acetate and Interferon in Relapsing-Remitting Multiple Sclerosis
por: Tacke, Sabine, et al.
Publicado: (2021)

Relapsing–Remitting Multiple Sclerosis Is Characterized by a T Follicular Cell Pro-Inflammatory Shift, Reverted by Dimethyl Fumarate Treatment
por: Cunill, Vanesa, et al.
Publicado: (2018)

Male and female are not the same: a multicenter study of static and dynamic functional connectivity in relapse-remitting multiple sclerosis in China
por: Wang, Yao, et al.
Publicado: (2023)

The Yin and Yang of IL-17 in Systemic Sclerosis
por: Wei, Lanxuan, et al.
Publicado: (2022)

Immunologic and MRI markers of the therapeutic effect of IFN-β-1a in relapsing-remitting MS
por: Tao, Yazhong, et al.
Publicado: (2015)

Postural Control in Relapsing-Remitting Multiple Sclerosis
por: Cusin, Flavia Salvaterra, et al.
Publicado: (2022)

Pro-Inflammatory Signaling by IL-10 and IL-22: Bad Habit Stirred Up by Interferons?
por: Mühl, Heiko
Publicado: (2013)

Th17 Cell-Mediated Colitis Is Positively Regulated by Interferon Regulatory Factor 4 in a T Cell-Extrinsic Manner
por: Buchele, Vera, et al.
Publicado: (2021)

Interleukin (IL)-12 and IL-18 Synergize to Promote MAIT Cell IL-17A and IL-17F Production Independently of IL-23 Signaling
por: Cole, Suzanne, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1emnk5cal5s21s4ml2cm8kb5ct