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Sulforaphane is a Nrf2-independent inhibitor of mitochondrial fission
The KEAP1-Nrf2-ARE antioxidant system is a principal means by which cells respond to oxidative and xenobiotic stresses. Sulforaphane (SFN), an electrophilic isothiocyanate derived from cruciferous vegetables, activates the KEAP1-Nrf2-ARE pathway and has become a molecule-of-interest in the treatment...
Autores principales: | O'Mealey, Gary B., Berry, William L., Plafker, Scott M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126150/ https://www.ncbi.nlm.nih.gov/pubmed/27889639 http://dx.doi.org/10.1016/j.redox.2016.11.007 |
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