The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non‐coding RNA and synonymous mutations

Cancer is a disease of the genome caused by oncogene activation and tumor suppressor gene inhibition. Deep sequencing studies including large consortia such as TCGA and ICGC identified numerous tumor‐specific mutations not only in protein‐coding sequences but also in non‐coding sequences. Although 9...

Descripción completa

Detalles Bibliográficos
Autores principales: Diederichs, Sven, Bartsch, Lorenz, Berkmann, Julia C, Fröse, Karin, Heitmann, Jana, Hoppe, Caroline, Iggena, Deetje, Jazmati, Danny, Karschnia, Philipp, Linsenmeier, Miriam, Maulhardt, Thomas, Möhrmann, Lino, Morstein, Johannes, Paffenholz, Stella V, Röpenack, Paula, Rückert, Timo, Sandig, Ludger, Schell, Maximilian, Steinmann, Anna, Voss, Gjendine, Wasmuth, Jacqueline, Weinberger, Maria E, Wullenkord, Ramona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126213/
https://www.ncbi.nlm.nih.gov/pubmed/26992833
http://dx.doi.org/10.15252/emmm.201506055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126213/
https://www.ncbi.nlm.nih.gov/pubmed/26992833
http://dx.doi.org/10.15252/emmm.201506055

Ejemplares similares