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A unified molecular mechanism for the regulation of acetyl-CoA carboxylase by phosphorylation
Acetyl-CoA carboxylases (ACCs) are crucial metabolic enzymes and attractive targets for drug discovery. Eukaryotic acetyl-CoA carboxylases are 250 kDa single-chain, multi-domain enzymes and function as dimers and higher oligomers. Their catalytic activity is tightly regulated by phosphorylation and...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126230/ https://www.ncbi.nlm.nih.gov/pubmed/27990296 http://dx.doi.org/10.1038/celldisc.2016.44 |
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Enlace del recurso
por Wei, Jia, Zhang, Yixiao, Yu, Tai-Yuan, Sadre-Bazzaz, Kianoush, Rudolph, Michael J, Amodeo, Gabriele A, Symington, Lorraine S, Walz, Thomas, Tong, Liang
Publicado 2017
Enlace del recurso
Publicado 2017
Enlace del recurso
Enlace del recurso
Online
Artículo
Texto