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Induction of heme oxygenase-1 with dietary quercetin reduces obesity-induced hepatic inflammation through macrophage phenotype switching

BACKGROUND/OBJECTIVES: Obesity-induced steatohepatitis accompanied by activated hepatic macrophages/Kupffer cells facilitates the progression of hepatic fibrinogenesis and exacerbates metabolic derangements such as insulin resistance. Heme oxyganase-1 (HO-1) modulates tissue macrophage phenotypes an...

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Detalles Bibliográficos
Autores principales: Kim, Chu-Sook, Choi, Hye-Seon, Joe, Yeonsoo, Chung, Hun Taeg, Yu, Rina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Nutrition Society and the Korean Society of Community Nutrition 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126412/
https://www.ncbi.nlm.nih.gov/pubmed/27909560
http://dx.doi.org/10.4162/nrp.2016.10.6.623

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