Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive immune activation that mimics and occurs with other systemic diseases. A 35-year-old female presented with signs of viral illness at 13 weeks of pregnancy and progressed to acute liver failure (ALF). We discuss the diagnosis of HLH...

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Detalles Bibliográficos
Autores principales: Giard, Jeanne-Marie, Decker, Kerry A., Lai, Jennifer C., Gill, Ryan M., Logan, Aaron C., Fix, Oren K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126497/
https://www.ncbi.nlm.nih.gov/pubmed/27921061
http://dx.doi.org/10.14309/crj.2016.135
Descripción
Sumario:Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive immune activation that mimics and occurs with other systemic diseases. A 35-year-old female presented with signs of viral illness at 13 weeks of pregnancy and progressed to acute liver failure (ALF). We discuss the diagnosis of HLH and Kikuchi-Fujimoto (KF) lymphadenitis in the context of pregnancy and ALF. HLH may respond to comorbid disease-specific therapy, and more toxic treatment can be avoided.

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