Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive immune activation that mimics and occurs with other systemic diseases. A 35-year-old female presented with signs of viral illness at 13 weeks of pregnancy and progressed to acute liver failure (ALF). We discuss the diagnosis of HLH...

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Autores principales: Giard, Jeanne-Marie, Decker, Kerry A., Lai, Jennifer C., Gill, Ryan M., Logan, Aaron C., Fix, Oren K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126497/
https://www.ncbi.nlm.nih.gov/pubmed/27921061
http://dx.doi.org/10.14309/crj.2016.135
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author Giard, Jeanne-Marie
Decker, Kerry A.
Lai, Jennifer C.
Gill, Ryan M.
Logan, Aaron C.
Fix, Oren K.
author_facet Giard, Jeanne-Marie
Decker, Kerry A.
Lai, Jennifer C.
Gill, Ryan M.
Logan, Aaron C.
Fix, Oren K.
author_sort Giard, Jeanne-Marie
collection PubMed
description Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive immune activation that mimics and occurs with other systemic diseases. A 35-year-old female presented with signs of viral illness at 13 weeks of pregnancy and progressed to acute liver failure (ALF). We discuss the diagnosis of HLH and Kikuchi-Fujimoto (KF) lymphadenitis in the context of pregnancy and ALF. HLH may respond to comorbid disease-specific therapy, and more toxic treatment can be avoided.
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spelling pubmed-51264972016-12-05 Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy Giard, Jeanne-Marie Decker, Kerry A. Lai, Jennifer C. Gill, Ryan M. Logan, Aaron C. Fix, Oren K. ACG Case Rep J Case Report Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive immune activation that mimics and occurs with other systemic diseases. A 35-year-old female presented with signs of viral illness at 13 weeks of pregnancy and progressed to acute liver failure (ALF). We discuss the diagnosis of HLH and Kikuchi-Fujimoto (KF) lymphadenitis in the context of pregnancy and ALF. HLH may respond to comorbid disease-specific therapy, and more toxic treatment can be avoided. American College of Gastroenterology 2016-11-23 /pmc/articles/PMC5126497/ /pubmed/27921061 http://dx.doi.org/10.14309/crj.2016.135 Text en Copyright © Giard et al. This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
Giard, Jeanne-Marie
Decker, Kerry A.
Lai, Jennifer C.
Gill, Ryan M.
Logan, Aaron C.
Fix, Oren K.
Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy
title Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy
title_full Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy
title_fullStr Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy
title_full_unstemmed Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy
title_short Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy
title_sort acute liver failure secondary to hemophagocytic lymphohistiocytosis during pregnancy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126497/
https://www.ncbi.nlm.nih.gov/pubmed/27921061
http://dx.doi.org/10.14309/crj.2016.135
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