Rapidly Progressive Muscle Paralysis and Acute Respiratory Failure Following Endoscopic Botulinum Toxin Injection

Botulism toxin injection (BTI) is a well-known and relatively safe endoscopic treatment for achalasia. We report a case of a 90-year-old female diagnosed with achalasia who subsequently underwent BTI with symptomatic relief. The therapy was complicated by systemic botulism, however, leading to progr...

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Detalles Bibliográficos
Autores principales: You, Geoffrey, Khan, Ahmed, Shor, Julia, Forester, Gary P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126502/
https://www.ncbi.nlm.nih.gov/pubmed/27921065
http://dx.doi.org/10.14309/crj.2016.139
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author You, Geoffrey
Khan, Ahmed
Shor, Julia
Forester, Gary P.
author_facet You, Geoffrey
Khan, Ahmed
Shor, Julia
Forester, Gary P.
author_sort You, Geoffrey
collection PubMed
description Botulism toxin injection (BTI) is a well-known and relatively safe endoscopic treatment for achalasia. We report a case of a 90-year-old female diagnosed with achalasia who subsequently underwent BTI with symptomatic relief. The therapy was complicated by systemic botulism, however, leading to progressive muscle paralysis with diaphragmatic involvement requiring mechanical ventilation support. This is the first reported case of BTI for achalasia causing systemic botulism.
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spelling pubmed-51265022016-12-05 Rapidly Progressive Muscle Paralysis and Acute Respiratory Failure Following Endoscopic Botulinum Toxin Injection You, Geoffrey Khan, Ahmed Shor, Julia Forester, Gary P. ACG Case Rep J Case Report Botulism toxin injection (BTI) is a well-known and relatively safe endoscopic treatment for achalasia. We report a case of a 90-year-old female diagnosed with achalasia who subsequently underwent BTI with symptomatic relief. The therapy was complicated by systemic botulism, however, leading to progressive muscle paralysis with diaphragmatic involvement requiring mechanical ventilation support. This is the first reported case of BTI for achalasia causing systemic botulism. American College of Gastroenterology 2016-11-23 /pmc/articles/PMC5126502/ /pubmed/27921065 http://dx.doi.org/10.14309/crj.2016.139 Text en Copyright © You et al. This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
You, Geoffrey
Khan, Ahmed
Shor, Julia
Forester, Gary P.
Rapidly Progressive Muscle Paralysis and Acute Respiratory Failure Following Endoscopic Botulinum Toxin Injection
title Rapidly Progressive Muscle Paralysis and Acute Respiratory Failure Following Endoscopic Botulinum Toxin Injection
title_full Rapidly Progressive Muscle Paralysis and Acute Respiratory Failure Following Endoscopic Botulinum Toxin Injection
title_fullStr Rapidly Progressive Muscle Paralysis and Acute Respiratory Failure Following Endoscopic Botulinum Toxin Injection
title_full_unstemmed Rapidly Progressive Muscle Paralysis and Acute Respiratory Failure Following Endoscopic Botulinum Toxin Injection
title_short Rapidly Progressive Muscle Paralysis and Acute Respiratory Failure Following Endoscopic Botulinum Toxin Injection
title_sort rapidly progressive muscle paralysis and acute respiratory failure following endoscopic botulinum toxin injection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126502/
https://www.ncbi.nlm.nih.gov/pubmed/27921065
http://dx.doi.org/10.14309/crj.2016.139
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