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TGF-β1 Induces Polypyrimidine Tract-Binding Protein to Alter Fibroblasts Proliferation and Fibronectin Deposition in Keloid

Human dermal fibrotic disease keloid has been a clinical challenge because of its tumour-like growth and the lack of effective therapy. Dysregulated alternative splicing events have been demonstrated in tumours and fibrosis. In the current study, for the first time, it was demonstrated that the spli...

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Detalles Bibliográficos
Autores principales: Jiao, Hu, Dong, Ping, Yan, Li, Yang, Zhigang, Lv, Xiaoyan, Li, Qiuchen, Zong, Xianlei, Fan, Jincai, Fu, Xin, Liu, Xia, Xiao, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126665/
https://www.ncbi.nlm.nih.gov/pubmed/27897224
http://dx.doi.org/10.1038/srep38033

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