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A Novel Therapeutic Peptide as a Partial Agonist of RANKL in Ischemic Stroke

The enhanced receptor activator of nuclear factor-κB (NFκB) ligand (RANKL) and its receptor (RANK) signal have been reported to attenuate ischemic brain injury through inhibition of Toll-like receptor (TLR) 4-mediated inflammation. However, augmentation of the RANKL/RANK signal also accelerates oste...

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Detalles Bibliográficos
Autores principales: Kurinami, Hitomi, Shimamura, Munehisa, Nakagami, Hironori, Shimizu, Hideo, Koriyama, Hiroshi, Kawano, Tomohiro, Wakayama, Kouji, Mochizuki, Hideki, Rakugi, Hiromi, Morishita, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126682/
https://www.ncbi.nlm.nih.gov/pubmed/27897273
http://dx.doi.org/10.1038/srep38062