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Identifying Cancer Driver Genes Using Replication-Incompetent Retroviral Vectors

Identifying novel genes that drive tumor metastasis and drug resistance has significant potential to improve patient outcomes. High-throughput sequencing approaches have identified cancer genes, but distinguishing driver genes from passengers remains challenging. Insertional mutagenesis screens usin...

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Detalles Bibliográficos
Autores principales:	Bii, Victor M., Trobridge, Grant D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126759/ https://www.ncbi.nlm.nih.gov/pubmed/27792127 http://dx.doi.org/10.3390/cancers8110099

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