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Gene Therapy: A Paradigm Shift in Dentistry
Gene therapy holds a promising future for bridging the gap between the disciplines of medicine and clinical dentistry. The dynamic treatment approaches of gene therapy have been advancing by leaps and bounds. They are transforming the conventional approaches into more precise and preventive ones tha...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126784/ https://www.ncbi.nlm.nih.gov/pubmed/27834914 http://dx.doi.org/10.3390/genes7110098 |
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author | Siddique, Nida Raza, Hira Ahmed, Sehrish Khurshid, Zohaib Zafar, Muhammad Sohail |
author_facet | Siddique, Nida Raza, Hira Ahmed, Sehrish Khurshid, Zohaib Zafar, Muhammad Sohail |
author_sort | Siddique, Nida |
collection | PubMed |
description | Gene therapy holds a promising future for bridging the gap between the disciplines of medicine and clinical dentistry. The dynamic treatment approaches of gene therapy have been advancing by leaps and bounds. They are transforming the conventional approaches into more precise and preventive ones that may limit the need of using drugs and surgery. The oral cavity is one of the most accessible areas for the clinical applications of gene therapy for various oral tissues. The idea of genetic engineering has become more exciting due to its advantages over other treatment modalities. For instance, the body is neither subjected to an invasive surgery nor deep wounds, nor is it susceptible to systemic effects of drugs. The aim of this article is to review the gene therapy applications in the field of dentistry. In addition, therapeutic benefits in terms of treatment of diseases, minimal invasion and maximum outcomes have been discussed. |
format | Online Article Text |
id | pubmed-5126784 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-51267842016-12-02 Gene Therapy: A Paradigm Shift in Dentistry Siddique, Nida Raza, Hira Ahmed, Sehrish Khurshid, Zohaib Zafar, Muhammad Sohail Genes (Basel) Review Gene therapy holds a promising future for bridging the gap between the disciplines of medicine and clinical dentistry. The dynamic treatment approaches of gene therapy have been advancing by leaps and bounds. They are transforming the conventional approaches into more precise and preventive ones that may limit the need of using drugs and surgery. The oral cavity is one of the most accessible areas for the clinical applications of gene therapy for various oral tissues. The idea of genetic engineering has become more exciting due to its advantages over other treatment modalities. For instance, the body is neither subjected to an invasive surgery nor deep wounds, nor is it susceptible to systemic effects of drugs. The aim of this article is to review the gene therapy applications in the field of dentistry. In addition, therapeutic benefits in terms of treatment of diseases, minimal invasion and maximum outcomes have been discussed. MDPI 2016-11-10 /pmc/articles/PMC5126784/ /pubmed/27834914 http://dx.doi.org/10.3390/genes7110098 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Siddique, Nida Raza, Hira Ahmed, Sehrish Khurshid, Zohaib Zafar, Muhammad Sohail Gene Therapy: A Paradigm Shift in Dentistry |
title | Gene Therapy: A Paradigm Shift in Dentistry |
title_full | Gene Therapy: A Paradigm Shift in Dentistry |
title_fullStr | Gene Therapy: A Paradigm Shift in Dentistry |
title_full_unstemmed | Gene Therapy: A Paradigm Shift in Dentistry |
title_short | Gene Therapy: A Paradigm Shift in Dentistry |
title_sort | gene therapy: a paradigm shift in dentistry |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126784/ https://www.ncbi.nlm.nih.gov/pubmed/27834914 http://dx.doi.org/10.3390/genes7110098 |
work_keys_str_mv | AT siddiquenida genetherapyaparadigmshiftindentistry AT razahira genetherapyaparadigmshiftindentistry AT ahmedsehrish genetherapyaparadigmshiftindentistry AT khurshidzohaib genetherapyaparadigmshiftindentistry AT zafarmuhammadsohail genetherapyaparadigmshiftindentistry |