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Burkholderia pseudomallei-derived miR-3473 enhances NF-κB via targeting TRAF3 and is associated with different inflammatory responses compared to Burkholderia thailandensis in murine macrophages

BACKGROUND: Burkholderia pseudomallei (Bp) is the causative agent of melioidosis, a kind of tropical disease. Burkholderia thailandensis (Bt), with a high sequence similarity to Bp, is thought to be an avirulent organism. Since there are numerous similarities between Bp and Bt, their differences in...

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Detalles Bibliográficos
Autores principales: Fang, Yao, Chen, Hai, Hu, Yi, Li, Qian, Hu, Zhiqiang, Ma, Tengfei, Mao, Xuhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126824/
https://www.ncbi.nlm.nih.gov/pubmed/27894256
http://dx.doi.org/10.1186/s12866-016-0901-6