Cargando…
Salidroside reduces tau hyperphosphorylation via up-regulating GSK-3β phosphorylation in a tau transgenic Drosophila model of Alzheimer’s disease
BACKGROUND: Alzheimer’s disease (AD) is an age-related and progressive neurodegenerative disease that causes substantial public health care burdens. Intensive efforts have been made to find effective and safe treatment against AD. Salidroside (Sal) is the main effective component of Rhodiola rosea L...
Autores principales: | Zhang, Bei, Li, Qiongqiong, Chu, Xingkun, Sun, Suya, Chen, Shengdi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126879/ https://www.ncbi.nlm.nih.gov/pubmed/27933142 http://dx.doi.org/10.1186/s40035-016-0068-y |
Ejemplares similares
-
Neuroprotective effects of salidroside through PI3K/Akt pathway activation in Alzheimer’s disease models
por: Zhang, Bei, et al.
Publicado: (2016) -
Identification of the Sites of Tau Hyperphosphorylation and Activation of Tau Kinases in Synucleinopathies and Alzheimer’s Diseases
por: Duka, Valeriy, et al.
Publicado: (2013) -
Site-Specific Cerebrospinal Fluid Tau Hyperphosphorylation in Response to Alzheimer’s Disease Brain Pathology: Not All Tau Phospho-Sites are Hyperphosphorylated
por: Barthélemy, Nicolas R., et al.
Publicado: (2022) -
Truncation and activation of GSK-3β by calpain I: a molecular mechanism links to tau hyperphosphorylation in Alzheimer's disease
por: Jin, Nana, et al.
Publicado: (2015) -
Hyperphosphorylation-Induced Tau Oligomers
por: Iqbal, Khalid, et al.
Publicado: (2013)