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Pathogens Inactivated by Low-Energy-Electron Irradiation Maintain Antigenic Properties and Induce Protective Immune Responses
Inactivated vaccines are commonly produced by incubating pathogens with chemicals such as formaldehyde or β-propiolactone. This is a time-consuming process, the inactivation efficiency displays high variability and extensive downstream procedures are often required. Moreover, application of chemical...
Autores principales: | Fertey, Jasmin, Bayer, Lea, Grunwald, Thomas, Pohl, Alexandra, Beckmann, Jana, Gotzmann, Gaby, Casado, Javier Portillo, Schönfelder, Jessy, Rögner, Frank-Holm, Wetzel, Christiane, Thoma, Martin, Bailer, Susanne M., Hiller, Ekkehard, Rupp, Steffen, Ulbert, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127033/ https://www.ncbi.nlm.nih.gov/pubmed/27886076 http://dx.doi.org/10.3390/v8110319 |
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