Head-and-neck squamous cell carcinoma risk in smokers: no association detected between phenotype and AHR, CYP1A1, CYP1A2, or CYP1B1 genotype

BACKGROUND: Head-and-neck squamous cell carcinoma (HNSCC) differs between smokers and nonsmokers in etiology and clinical presentation. Because of demonstrated unequivocal involvement in smoking-induced cancer in laboratory animals, four candidate genes––AHR, CYP1A1, CYP1A2, and CYP1B1––were selecte...

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Detalles Bibliográficos
Autores principales: Jorge-Nebert, Lucia F., Zhang, Ge, Wilson, Keith M., Jiang, Zhengwen, Butler, Randall, Gluckman, Jack L., Pinney, Susan M., Nebert, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127090/
https://www.ncbi.nlm.nih.gov/pubmed/27894333
http://dx.doi.org/10.1186/s40246-016-0094-y

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