Cargando…

Effect of Fusarium-Derived Metabolites on the Barrier Integrity of Differentiated Intestinal Porcine Epithelial Cells (IPEC-J2)

The human, animal and plant pathogen Fusarium, which contaminates agricultural commodities worldwide, produces numerous secondary metabolites. An example is the thoroughly-investigated deoxynivalenol (DON), which severely impairs gastrointestinal barrier integrity. However, to date, the toxicologica...

Descripción completa

Detalles Bibliográficos
Autores principales:	Springler, Alexandra, Vrubel, Galina-Jacqueline, Mayer, Elisabeth, Schatzmayr, Gerd, Novak, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127141/ https://www.ncbi.nlm.nih.gov/pubmed/27869761 http://dx.doi.org/10.3390/toxins8110345

Ejemplares similares

Early Activation of MAPK p44/42 Is Partially Involved in DON-Induced Disruption of the Intestinal Barrier Function and Tight Junction Network
por: Springler, Alexandra, et al.
Publicado: (2016)

Infection of Porcine Circovirus 2 (PCV2) in Intestinal Porcine Epithelial Cell Line (IPEC-J2) and Interaction between PCV2 and IPEC-J2 Microfilaments
por: Yan, Mengfei, et al.
Publicado: (2014)

Effect of probiotic bacteria on porcine rotavirus OSU infection of porcine intestinal epithelial IPEC-J2 cells
por: Leblanc, Danielle, et al.
Publicado: (2022)

Deoxynivalenol and its metabolite deepoxy-deoxynivalenol: multi-parameter analysis for the evaluation of cytotoxicity and cellular effects
por: Springler, Alexandra, et al.
Publicado: (2016)

Gene Regulation of Intestinal Porcine Epithelial Cells IPEC-J2 Is Dependent on the Site of Deoxynivalenol Toxicological Action
por: Diesing, Anne-Kathrin, et al.
Publicado: (2012)

Concerted action of berberine in the porcine intestinal epithelial model IPEC‐J2: Effects on tight junctions and apoptosis
por: Cornelius, Valeria, et al.
Publicado: (2022)

Susceptibility of porcine IPEC-J2 intestinal epithelial cells to infection with porcine deltacoronavirus (PDCoV) and serum cytokine responses of gnotobiotic pigs to acute infection with IPEC-J2 cell culture-passaged PDCoV
por: Jung, Kwonil, et al.
Publicado: (2018)

Deoxynivalenol Inhibits Porcine Intestinal Trefoil Factors Expression in Weanling Piglets and IPEC-J2 Cells
por: Wang, Shuai, et al.
Publicado: (2019)

Comparing Two Intestinal Porcine Epithelial Cell Lines (IPECs): Morphological Differentiation, Function and Metabolism
por: Nossol, Constanze, et al.
Publicado: (2015)

Deoxynivalenol Affects Cell Metabolism and Increases Protein Biosynthesis in Intestinal Porcine Epithelial Cells (IPEC-J2): DON Increases Protein Biosynthesis
por: Nossol, Constanze, et al.
Publicado: (2018)

Antioxidant Activity of Flavonoids in LPS-Treated IPEC-J2 Porcine Intestinal Epithelial Cells and Their Antibacterial Effect against Bacteria of Swine Origin
por: Kovács, Dóra, et al.
Publicado: (2020)

Bovine Peripheral Blood Mononuclear Cells Are More Sensitive to Deoxynivalenol Than Those Derived from Poultry and Swine
por: Novak, Barbara, et al.
Publicado: (2018)

Effects of deoxynivalenol (DON) and its microbial biotransformation product deepoxy-deoxynivalenol (DOM-1) on a trout, pig, mouse, and human cell line
por: Mayer, Elisabeth, et al.
Publicado: (2017)

Tannic Acid Induces the Mitochondrial Pathway of Apoptosis and S Phase Arrest in Porcine Intestinal IPEC-J2 Cells
por: Wang, Ji, et al.
Publicado: (2019)

Deoxynivalenol Impairs Porcine Intestinal Host Defense Peptide Expression in Weaned Piglets and IPEC-J2 Cells
por: Wang, Shuai, et al.
Publicado: (2018)

Effects of 1,2-Dimethylhydrazine on Barrier Properties of Rat Large Intestine and IPEC-J2 Cells
por: Bekusova, Viktoria, et al.
Publicado: (2021)

Physiological Concentration of Exogenous Lactate Reduces Antimycin A Triggered Oxidative Stress in Intestinal Epithelial Cell Line IPEC-1 and IPEC-J2 In Vitro
por: Kahlert, Stefan, et al.
Publicado: (2016)

Protective Role of Hydrogen Gas on Oxidative Damage and Apoptosis in Intestinal Porcine Epithelial Cells (IPEC-J2) Induced by Deoxynivalenol: A Preliminary Study
por: Ji, Xu, et al.
Publicado: (2019)

Air–liquid interface enhances oxidative phosphorylation in intestinal epithelial cell line IPEC-J2
por: Klasvogt, Sonja, et al.
Publicado: (2017)

TGF-β from the Porcine Intestinal Cell Line IPEC-J2 Induced by Porcine Circovirus 2 Increases the Frequency of Treg Cells via the Activation of ERK (in CD4(+) T Cells) and NF-κB (in IPEC-J2)
por: Liu, Xuewei, et al.
Publicado: (2022)

Comparison of expression profiles between undifferentiated and differentiated porcine IPEC-J2 cells
por: Pi, Guolin, et al.
Publicado: (2022)

Polymethoxyflavone Apigenin-Trimethylether Suppresses LPS-Induced Inflammatory Response in Nontransformed Porcine Intestinal Cell Line IPEC-J2
por: Farkas, Orsolya, et al.
Publicado: (2015)

Tannic acid attenuates intestinal oxidative damage by improving antioxidant capacity and intestinal barrier in weaned piglets and IPEC-J2 cells
por: Wang, Meiwei, et al.
Publicado: (2022)

Twenty-Eight Fungal Secondary Metabolites Detected in Pig Feed Samples: Their Occurrence, Relevance and Cytotoxic Effects In Vitro
por: Novak, Barbara, et al.
Publicado: (2019)

Improved Cell Line IPEC-J2, Characterized as a Model for Porcine Jejunal Epithelium
por: Zakrzewski, Silke S., et al.
Publicado: (2013)

S100A9 plays a key role in Clostridium perfringens beta2 toxin-induced inflammatory damage in porcine IPEC-J2 intestinal epithelial cells
por: Li, Jie, et al.
Publicado: (2023)

Air–liquid interface cultures enhance the oxygen supply and trigger the structural and functional differentiation of intestinal porcine epithelial cells (IPEC)
por: Nossol, Constanze, et al.
Publicado: (2011)

Zearalenone-Induced Mechanical Damage of Intestinal Barrier via the RhoA/ROCK Signaling Pathway in IPEC-J2 Cells
por: Huang, Biying, et al.
Publicado: (2022)

The profiles of mitochondrial respiration and glycolysis using extracellular flux analysis in porcine enterocyte IPEC-J2
por: Tan, Bie, et al.
Publicado: (2015)

Lactobacillus reuteri strains protect epithelial barrier integrity of IPEC‐J2 monolayers from the detrimental effect of enterotoxigenic Escherichia coli
por: Karimi, Shokoufeh, et al.
Publicado: (2018)

AMPK-PINK1/Parkin Mediated Mitophagy Is Necessary for Alleviating Oxidative Stress-Induced Intestinal Epithelial Barrier Damage and Mitochondrial Energy Metabolism Dysfunction in IPEC-J2
por: Cao, Shuting, et al.
Publicado: (2021)

Porcine intestinal epithelial barrier disruption by the Fusarium mycotoxins deoxynivalenol and T-2 toxin promotes transepithelial passage of doxycycline and paromomycin
por: Goossens, Joline, et al.
Publicado: (2012)

Preliminary Characterization of the Transcriptional Response of the Porcine Intestinal Cell Line IPEC-J2 to Enterotoxigenic Escherichia coli, Escherichia coli, and E. coli Lipopolysaccharide
por: Geens, Marisa M., et al.
Publicado: (2010)

Lack of LTβR Increases Susceptibility of IPEC-J2 Cells to Porcine Epidemic Diarrhea Virus
por: Altawaty, Tawfeek, et al.
Publicado: (2018)

Influence of phytogenics on recovery of the barrier function of intestinal porcine epithelial cells after a calcium switch
por: Bachinger, Diana, et al.
Publicado: (2018)

Quercetin attenuates deoxynivalenol-induced intestinal barrier dysfunction by activation of Nrf2 signaling pathway in IPEC-J2 cells and weaned piglets
por: Li, Enkai, et al.
Publicado: (2023)

4-Phenylbutyric acid accelerates rehabilitation of barrier function in IPEC-J2 cell monolayer model
por: Jiang, Qian, et al.
Publicado: (2021)

A Co-Culture Model of IPEC-J2 and Swine PBMC to Study the Responsiveness of Intestinal Epithelial Cells: The Regulatory Effect of Arginine Deprivation
por: Saleri, Roberta, et al.
Publicado: (2021)

Chenodeoxycholic Acid (CDCA) Promoted Intestinal Epithelial Cell Proliferation by Regulating Cell Cycle Progression and Mitochondrial Biogenesis in IPEC-J2 Cells
por: Xu, Lei, et al.
Publicado: (2022)

Differences in cytokines expression between Vero cells and IPEC-J2 cells infected with porcine epidemic diarrhea virus
por: Yuan, Chen, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_q9e1e7pp73fb8hkutj7jdqmiqf