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The effects of old and recent migration waves in the distribution of HBB*S globin gene haplotypes
Sickle cell hemoglobin is the result of a mutation at the sixth amino acid position of the beta (β) globin chain. The HBB*S gene is in linkage disequilibrium with five main haplotypes in the β-globin-like gene cluster named according to their ethnic and geographic origins: Bantu (CAR), Benin (BEN),...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Genética
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127156/ https://www.ncbi.nlm.nih.gov/pubmed/27706371 http://dx.doi.org/10.1590/1678-4685-GMB-2016-0032 |