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The effects of old and recent migration waves in the distribution of HBB*S globin gene haplotypes

Sickle cell hemoglobin is the result of a mutation at the sixth amino acid position of the beta (β) globin chain. The HBB*S gene is in linkage disequilibrium with five main haplotypes in the β-globin-like gene cluster named according to their ethnic and geographic origins: Bantu (CAR), Benin (BEN),...

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Detalles Bibliográficos
Autores principales: Lindenau, Juliana D., Wagner, Sandrine C., de Castro, Simone M., Hutz, Mara H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127156/
https://www.ncbi.nlm.nih.gov/pubmed/27706371
http://dx.doi.org/10.1590/1678-4685-GMB-2016-0032