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High‐throughput screening of clinically approved drugs that prime polyethylenimine transfection reveals modulation of mitochondria dysfunction response improves gene transfer efficiencies

Nonviral gene delivery methods are advantageous over viral vectors in terms of safety, cost, and flexibility in design and application, but suffer from lower gene transfer efficiency. In addition to modifications to nucleic acid design and nonviral carriers, new tools are sought to enhance transfect...

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Detalles Bibliográficos
Autores principales: Nguyen, Albert, Beyersdorf, Jared, Riethoven, Jean‐Jack, Pannier, Angela K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127179/
https://www.ncbi.nlm.nih.gov/pubmed/27981241
http://dx.doi.org/10.1002/btm2.10017

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