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Toll-Like Receptor 4 Activation Contributes to Diabetic Bladder Dysfunction in a Murine Model of Type 1 Diabetes
Diabetic bladder dysfunction (DBD) is a common urological complication of diabetes. Innate immune system activation via Toll-like receptor 4 (TLR4) leads to inflammation and oxidative stress and was implicated in diabetes pathophysiology. We hypothesized that bladder hypertrophy and hypercontractili...
Autores principales: | Szasz, Theodora, Wenceslau, Camilla F., Burgess, Beth, Nunes, Kenia P., Webb, R. Clinton |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127246/ https://www.ncbi.nlm.nih.gov/pubmed/27650857 http://dx.doi.org/10.2337/db16-0480 |
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