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Growth Hormone Control of Hepatic Lipid Metabolism
In humans, low levels of growth hormone (GH) and its mediator, IGF-1, associate with hepatic lipid accumulation. In mice, congenital liver-specific ablation of the GH receptor (GHR) results in reductions in circulating IGF-1 and hepatic steatosis, associated with systemic insulin resistance. Due to...
Autores principales: | Liu, Zhongbo, Cordoba-Chacon, Jose, Kineman, Rhonda D., Cronstein, Bruce N., Muzumdar, Radhika, Gong, Zhenwei, Werner, Haim, Yakar, Shoshana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127251/ https://www.ncbi.nlm.nih.gov/pubmed/27679560 http://dx.doi.org/10.2337/db16-0649 |
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