Cargando…
Molecular Dynamics Study of Twister Ribozyme: Role of Mg(2+) Ions and the Hydrogen-Bonding Network in the Active Site
[Image: see text] The recently discovered twister ribozyme is thought to utilize general acid–base catalysis in its self-cleavage mechanism, but the roles of nucleobases and metal ions in the mechanism are unclear. Herein, molecular dynamics simulations of the env22 twister ribozyme are performed to...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2016
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127262/ https://www.ncbi.nlm.nih.gov/pubmed/27295275 http://dx.doi.org/10.1021/acs.biochem.6b00203 |