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Recurrent radiation-induced osteosarcoma of the sternum in a patient with remote radiation therapy for breast cancer

BACKGROUND: Recurrent radiation-induced osteosarcoma of the sternum following remote radiation therapy for breast cancer and sternal reconstruction. CASE: A 51-year-old woman presents with recurrent, radiation-induced sternal osteosarcoma 11 years after receiving both radiation therapy for breast ca...

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Detalles Bibliográficos
Autores principales: Limback, Joseph M., Letter, Haley P., Scherer, Kurt F., Wasyliw, Christopher W., Bancroft, Laura W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128365/
https://www.ncbi.nlm.nih.gov/pubmed/27920865
http://dx.doi.org/10.1016/j.radcr.2016.06.002
Descripción
Sumario:BACKGROUND: Recurrent radiation-induced osteosarcoma of the sternum following remote radiation therapy for breast cancer and sternal reconstruction. CASE: A 51-year-old woman presents with recurrent, radiation-induced sternal osteosarcoma 11 years after receiving both radiation therapy for breast cancer and sternal reconstruction. The case details both her work-up and subsequent course, including reconstructive and curative efforts. DISCUSSION: An uncommon side effect of radiation therapy for breast cancer is development of osteosarcoma of the chest wall. Even rarer is recurrence of the osteosarcoma following sternal reconstruction.