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Primary hepatic malignant peripheral nerve sheath tumor successfully treated with combination therapy: a case report and literature review
Primary malignant peripheral nerve sheath tumor (MPNST) in a young female patient, not associated with neurofibromatosis type-I is extremely rare in the liver. A 33-year-old female was admitted with a right flank pain for a weak. The CT scan showed 12.5-cm-sized mass located at the right hepatic lob...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Surgical Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128380/ https://www.ncbi.nlm.nih.gov/pubmed/27904856 http://dx.doi.org/10.4174/astr.2016.91.6.327 |
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author | Jung, Hae Il Lee, Hyoung Uk Ahn, Tae Sung Lee, Jong Eun Lee, Hyun Yong Cho, Hyon Doek Lee, Sang Cheol Bae, Sang Ho |
author_facet | Jung, Hae Il Lee, Hyoung Uk Ahn, Tae Sung Lee, Jong Eun Lee, Hyun Yong Cho, Hyon Doek Lee, Sang Cheol Bae, Sang Ho |
author_sort | Jung, Hae Il |
collection | PubMed |
description | Primary malignant peripheral nerve sheath tumor (MPNST) in a young female patient, not associated with neurofibromatosis type-I is extremely rare in the liver. A 33-year-old female was admitted with a right flank pain for a weak. The CT scan showed 12.5-cm-sized mass located at the right hepatic lobe. At laparotomy, about 20.0-cm-sized mass was on the right hepatic lobe with attachment to right diaphragmatic pleura. Right hepatic lobe and adherent part of diaphragmatic pleura were resected. On histology and immunohistochemistry, it was diagnosed MPNST. Adjuvant radiotherapy for the right diaphragmatic pleura and adjuvant chemotherapy with adriamycin, ifosfamide and cisplatin were sequentially performed. The prognosis of MPNST is generally poor and it is associated with a highly aggressive course of recurrence, metastases, and death. Our case is probably a first report about combination therapy. |
format | Online Article Text |
id | pubmed-5128380 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The Korean Surgical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-51283802016-12-01 Primary hepatic malignant peripheral nerve sheath tumor successfully treated with combination therapy: a case report and literature review Jung, Hae Il Lee, Hyoung Uk Ahn, Tae Sung Lee, Jong Eun Lee, Hyun Yong Cho, Hyon Doek Lee, Sang Cheol Bae, Sang Ho Ann Surg Treat Res Case Report Primary malignant peripheral nerve sheath tumor (MPNST) in a young female patient, not associated with neurofibromatosis type-I is extremely rare in the liver. A 33-year-old female was admitted with a right flank pain for a weak. The CT scan showed 12.5-cm-sized mass located at the right hepatic lobe. At laparotomy, about 20.0-cm-sized mass was on the right hepatic lobe with attachment to right diaphragmatic pleura. Right hepatic lobe and adherent part of diaphragmatic pleura were resected. On histology and immunohistochemistry, it was diagnosed MPNST. Adjuvant radiotherapy for the right diaphragmatic pleura and adjuvant chemotherapy with adriamycin, ifosfamide and cisplatin were sequentially performed. The prognosis of MPNST is generally poor and it is associated with a highly aggressive course of recurrence, metastases, and death. Our case is probably a first report about combination therapy. The Korean Surgical Society 2016-12 2016-11-25 /pmc/articles/PMC5128380/ /pubmed/27904856 http://dx.doi.org/10.4174/astr.2016.91.6.327 Text en Copyright © 2016, the Korean Surgical Society http://creativecommons.org/licenses/by-nc/4.0/ Annals of Surgical Treatment and Research is an Open Access Journal. All articles are distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Jung, Hae Il Lee, Hyoung Uk Ahn, Tae Sung Lee, Jong Eun Lee, Hyun Yong Cho, Hyon Doek Lee, Sang Cheol Bae, Sang Ho Primary hepatic malignant peripheral nerve sheath tumor successfully treated with combination therapy: a case report and literature review |
title | Primary hepatic malignant peripheral nerve sheath tumor successfully treated with combination therapy: a case report and literature review |
title_full | Primary hepatic malignant peripheral nerve sheath tumor successfully treated with combination therapy: a case report and literature review |
title_fullStr | Primary hepatic malignant peripheral nerve sheath tumor successfully treated with combination therapy: a case report and literature review |
title_full_unstemmed | Primary hepatic malignant peripheral nerve sheath tumor successfully treated with combination therapy: a case report and literature review |
title_short | Primary hepatic malignant peripheral nerve sheath tumor successfully treated with combination therapy: a case report and literature review |
title_sort | primary hepatic malignant peripheral nerve sheath tumor successfully treated with combination therapy: a case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128380/ https://www.ncbi.nlm.nih.gov/pubmed/27904856 http://dx.doi.org/10.4174/astr.2016.91.6.327 |
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