Cargando…
Association of Endoscopic Features of Gastric Mucosa with Helicobacter pylori Infection in Chinese Patients
The aim of this study is to identify and consolidate reliable endoscopic features associated with H. pylori infection in gastric mucosa, which is one of the major causes of gastric cancer. A total of 256 Chinese patients with symptomatic stomach disturbances were enrolled. Pathological examination w...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128703/ https://www.ncbi.nlm.nih.gov/pubmed/27974885 http://dx.doi.org/10.1155/2016/6539639 |
_version_ | 1782470454376660992 |
---|---|
author | Mao, Tao Wang, Yan Yin, Fan Zhao, Qingxi Yang, Lin Ding, Xueli Tian, Zibin |
author_facet | Mao, Tao Wang, Yan Yin, Fan Zhao, Qingxi Yang, Lin Ding, Xueli Tian, Zibin |
author_sort | Mao, Tao |
collection | PubMed |
description | The aim of this study is to identify and consolidate reliable endoscopic features associated with H. pylori infection in gastric mucosa, which is one of the major causes of gastric cancer. A total of 256 Chinese patients with symptomatic stomach disturbances were enrolled. Pathological examination was conducted using a light microscope and biopsy specimens stained with hematoxylin-eosin. Endoscopic examination was performed using a high resolution video endoscope. The association between endoscopic features and pathological H. pylori diagnosis was compared, and endoscopic features significantly associated with H. pylori infection were identified. A total of 14 endoscopic features were observed. Six of the 14 endoscopic features, including mucus on the gastric mucosa, diffuse redness, spotty redness of fundic mucosa, enlarged fold, mucosal edema, and RAC (type D and type I), were highly associated with H. pylori infection and were significantly sensitive and specific predictors for H. pylori diagnosis. The type R RAC was not significantly associated with H. pylori diagnosis. Our results indicate that conventional endoscopy features can be used to diagnose H. pylori in Chinese patients and can help determine the risk factor for gastric cancer. |
format | Online Article Text |
id | pubmed-5128703 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-51287032016-12-14 Association of Endoscopic Features of Gastric Mucosa with Helicobacter pylori Infection in Chinese Patients Mao, Tao Wang, Yan Yin, Fan Zhao, Qingxi Yang, Lin Ding, Xueli Tian, Zibin Gastroenterol Res Pract Research Article The aim of this study is to identify and consolidate reliable endoscopic features associated with H. pylori infection in gastric mucosa, which is one of the major causes of gastric cancer. A total of 256 Chinese patients with symptomatic stomach disturbances were enrolled. Pathological examination was conducted using a light microscope and biopsy specimens stained with hematoxylin-eosin. Endoscopic examination was performed using a high resolution video endoscope. The association between endoscopic features and pathological H. pylori diagnosis was compared, and endoscopic features significantly associated with H. pylori infection were identified. A total of 14 endoscopic features were observed. Six of the 14 endoscopic features, including mucus on the gastric mucosa, diffuse redness, spotty redness of fundic mucosa, enlarged fold, mucosal edema, and RAC (type D and type I), were highly associated with H. pylori infection and were significantly sensitive and specific predictors for H. pylori diagnosis. The type R RAC was not significantly associated with H. pylori diagnosis. Our results indicate that conventional endoscopy features can be used to diagnose H. pylori in Chinese patients and can help determine the risk factor for gastric cancer. Hindawi Publishing Corporation 2016 2016-11-16 /pmc/articles/PMC5128703/ /pubmed/27974885 http://dx.doi.org/10.1155/2016/6539639 Text en Copyright © 2016 Tao Mao et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Mao, Tao Wang, Yan Yin, Fan Zhao, Qingxi Yang, Lin Ding, Xueli Tian, Zibin Association of Endoscopic Features of Gastric Mucosa with Helicobacter pylori Infection in Chinese Patients |
title | Association of Endoscopic Features of Gastric Mucosa with Helicobacter pylori Infection in Chinese Patients |
title_full | Association of Endoscopic Features of Gastric Mucosa with Helicobacter pylori Infection in Chinese Patients |
title_fullStr | Association of Endoscopic Features of Gastric Mucosa with Helicobacter pylori Infection in Chinese Patients |
title_full_unstemmed | Association of Endoscopic Features of Gastric Mucosa with Helicobacter pylori Infection in Chinese Patients |
title_short | Association of Endoscopic Features of Gastric Mucosa with Helicobacter pylori Infection in Chinese Patients |
title_sort | association of endoscopic features of gastric mucosa with helicobacter pylori infection in chinese patients |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128703/ https://www.ncbi.nlm.nih.gov/pubmed/27974885 http://dx.doi.org/10.1155/2016/6539639 |
work_keys_str_mv | AT maotao associationofendoscopicfeaturesofgastricmucosawithhelicobacterpyloriinfectioninchinesepatients AT wangyan associationofendoscopicfeaturesofgastricmucosawithhelicobacterpyloriinfectioninchinesepatients AT yinfan associationofendoscopicfeaturesofgastricmucosawithhelicobacterpyloriinfectioninchinesepatients AT zhaoqingxi associationofendoscopicfeaturesofgastricmucosawithhelicobacterpyloriinfectioninchinesepatients AT yanglin associationofendoscopicfeaturesofgastricmucosawithhelicobacterpyloriinfectioninchinesepatients AT dingxueli associationofendoscopicfeaturesofgastricmucosawithhelicobacterpyloriinfectioninchinesepatients AT tianzibin associationofendoscopicfeaturesofgastricmucosawithhelicobacterpyloriinfectioninchinesepatients |