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3D-CLEM Reveals that a Major Portion of Mitotic Chromosomes Is Not Chromatin
Recent studies have revealed the importance of Ki-67 and the chromosome periphery in chromosome structure and segregation, but little is known about this elusive chromosome compartment. Here we used correlative light and serial block-face scanning electron microscopy, which we term 3D-CLEM, to model...
Autores principales: | Booth, Daniel G., Beckett, Alison J., Molina, Oscar, Samejima, Itaru, Masumoto, Hiroshi, Kouprina, Natalay, Larionov, Vladimir, Prior, Ian A., Earnshaw, William C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128728/ https://www.ncbi.nlm.nih.gov/pubmed/27840028 http://dx.doi.org/10.1016/j.molcel.2016.10.009 |
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