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The Sequestration of Oxy-Polybrominated Diphenyl Ethers in the Nudibranchs Miamira magnifica and Miamira miamirana

A series of oxy-polybrominated diphenyl ethers (O-PBDEs) has been isolated from the extracts of Miamira magnifica and Miamira miamirana collected from Queensland, Australia. M. magnifica sequesters the new OH-PBDE 1 and six known OH-PBDEs containing four to six bromines (2–7). M. miamirana also accu...

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Detalles Bibliográficos
Autores principales: Dewi, Ariyanti S., Cheney, Karen L., Urquhart, Holly H., Blanchfield, Joanne T., Garson, Mary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128741/
https://www.ncbi.nlm.nih.gov/pubmed/27801777
http://dx.doi.org/10.3390/md14110198
Descripción
Sumario:A series of oxy-polybrominated diphenyl ethers (O-PBDEs) has been isolated from the extracts of Miamira magnifica and Miamira miamirana collected from Queensland, Australia. M. magnifica sequesters the new OH-PBDE 1 and six known OH-PBDEs containing four to six bromines (2–7). M. miamirana also accumulates known tribromo- and tetrabromo OMe-PBDEs 8–10 in both mantle and viscera tissues. To date, Miamira is the only genus of the family Chromodorididae that is known to incorporate O-PBDEs, rather than terpenes, in the mantle where the metabolites may play a putative role in chemical defense. The extract of M. magnifica was tested in a brine shrimp lethality assay and exhibited an LD(50) of 58 μg/mL.