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Structure–Activity Relationship Studies Using Natural and Synthetic Okadaic Acid/Dinophysistoxin Toxins

Okadaic acid (OA) and the closely related dinophysistoxins (DTXs) are algal toxins that accumulate in shellfish and are known serine/threonine protein phosphatase (ser/thr PP) inhibitors. Phosphatases are important modulators of enzyme activity and cell signaling pathways. However, the interactions...

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Detalles Bibliográficos
Autores principales:	Twiner, Michael J., Doucette, Gregory J., Pang, Yucheng, Fang, Chao, Forsyth, Craig J., Miles, Christopher O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128750/ https://www.ncbi.nlm.nih.gov/pubmed/27827901 http://dx.doi.org/10.3390/md14110207

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