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Anti-Melanogenic Activity of Gagunin D, a Highly Oxygenated Diterpenoid from the Marine Sponge Phorbas sp., via Modulating Tyrosinase Expression and Degradation

Tyrosinase is the rate-limiting enzyme critical for melanin synthesis and controls pigmentation in the skin. The inhibition of tyrosinase is currently the most common approach for the development of skin-whitening cosmetics. Gagunin D (GD), a highly oxygenated diterpenoid isolated from the marine sp...

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Detalles Bibliográficos
Autores principales: Lee, Ho Yeon, Jang, Eun Jeong, Bae, Song Yi, Jeon, Ju-eun, Park, Hyen Joo, Shin, Jongheon, Lee, Sang Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128755/
https://www.ncbi.nlm.nih.gov/pubmed/27869664
http://dx.doi.org/10.3390/md14110212

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