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Anti-Melanogenic Activity of Gagunin D, a Highly Oxygenated Diterpenoid from the Marine Sponge Phorbas sp., via Modulating Tyrosinase Expression and Degradation
Tyrosinase is the rate-limiting enzyme critical for melanin synthesis and controls pigmentation in the skin. The inhibition of tyrosinase is currently the most common approach for the development of skin-whitening cosmetics. Gagunin D (GD), a highly oxygenated diterpenoid isolated from the marine sp...
Autores principales: | Lee, Ho Yeon, Jang, Eun Jeong, Bae, Song Yi, Jeon, Ju-eun, Park, Hyen Joo, Shin, Jongheon, Lee, Sang Kook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128755/ https://www.ncbi.nlm.nih.gov/pubmed/27869664 http://dx.doi.org/10.3390/md14110212 |
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