Greater efficacy of atorvastatin versus a non-statin lipid-lowering agent against renal injury: potential role as a histone deacetylase inhibitor

Statins, 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors have been shown to improve diabetic nephropathy. However, whether they provide protection via Histone deacetylases (HDAC) inhibition is not clear. We conducted a comparative evaluation of Atorvastatin (AT) versus the non-statin cho...

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Detalles Bibliográficos
Autores principales: Singh, Ravi Shankar, Chaudhary, Dharmendra Kumar, Mohan, Aradhana, Kumar, Praveen, Chaturvedi, Chandra Prakash, Ecelbarger, Carolyn M., Godbole, Madan M., Tiwari, Swasti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128790/
https://www.ncbi.nlm.nih.gov/pubmed/27901066
http://dx.doi.org/10.1038/srep38034

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