HUWE1 plays important role in mouse preimplantation embryo development and the dysregulation is associated with poor embryo development in humans

HUWE1 is a HECT domain containing ubiquitin ligase implicated in neurogenesis, spermatogenesis and cancer development. The purpose of the current study is to investigate the role of HUWE1 in early embryo development. Here we demonstrate that Huwe1 is expressed in both nucleus and cytoplasm of preimp...

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Detalles Bibliográficos
Autores principales: Chen, L. J., Xu, W. M., Yang, M., Wang, K., Chen, Y., Huang, X. J., Ma, Q. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128802/
https://www.ncbi.nlm.nih.gov/pubmed/27901130
http://dx.doi.org/10.1038/srep37928

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