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Functional defects in CD4(+) CD25(high) FoxP3(+) regulatory cells in ankylosing spondylitis

Forkhead box P3 (FoxP3)-positive regulatory T cells (Tregs) play a pivotal role in the preservation of self-tolerance, and Treg dysfunction has been implicated in many autoimmune diseases. Whether and how Tregs participate in the pathogenesis of ankylosing spondylitis (AS) has not been fully elucida...

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Detalles Bibliográficos
Autores principales:	Guo, Huifang, Zheng, Ming, Zhang, Kui, Yang, Fengfan, Zhang, Xin, Han, Qing, Chen, Zhi-Nan, Zhu, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128857/ https://www.ncbi.nlm.nih.gov/pubmed/27901054 http://dx.doi.org/10.1038/srep37559

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