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Targeted killing of myofibroblasts by biosurfactant di-rhamnolipid suggests a therapy against scar formation

Pathological myofibroblasts are often involved in skin scarring via generating contractile force and over-expressing collagen fibers, but no compound has been found to inhibit the myofibroblasts without showing severe toxicity to surrounding physiological cells. Here we report that di-rhamnolipid, a...

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Detalles Bibliográficos
Autores principales: Shen, Chong, Jiang, Lifang, Shao, Huawei, You, Chuangang, Zhang, Guoliang, Ding, Sitong, Bian, Tingwei, Han, Chunmao, Meng, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128858/
https://www.ncbi.nlm.nih.gov/pubmed/27901027
http://dx.doi.org/10.1038/srep37553