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Thyroid metastasis from lung adenocarcinoma with EML4-ALK rearrangement
Thyroid metastases from lung cancer are very rare. A woman aged 42 years with a tumour in the lower lobe of the right lung was diagnosed as having lung adenocarcinoma positive for echinoderm microtubule-associated proteinlike 4-anaplastic lymphoma kinase. Positron emission tomography demonstrated fl...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128885/ https://www.ncbi.nlm.nih.gov/pubmed/27872133 http://dx.doi.org/10.1136/bcr-2016-217541 |
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author | Kawamoto, Hironori Kaneko, Yugo Ryu, Kai Kuwano, Kazuyoshi |
author_facet | Kawamoto, Hironori Kaneko, Yugo Ryu, Kai Kuwano, Kazuyoshi |
author_sort | Kawamoto, Hironori |
collection | PubMed |
description | Thyroid metastases from lung cancer are very rare. A woman aged 42 years with a tumour in the lower lobe of the right lung was diagnosed as having lung adenocarcinoma positive for echinoderm microtubule-associated proteinlike 4-anaplastic lymphoma kinase. Positron emission tomography demonstrated fluorodeoxyglucose accumulation in the lower lobe of the right lung, the right thyroid lobe and both adrenal glands. We performed fine-needle aspiration biopsy (FNAB) and used reverse transcriptase-PCR (RT-PCR) to diagnose the patient as having metastatic lung adenocarcinoma to the thyroid gland. We believe that FNAB combined with RT-PCR can be an effective method for diagnosing metastatic lung adenocarcinoma to the thyroid gland. |
format | Online Article Text |
id | pubmed-5128885 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-51288852016-12-08 Thyroid metastasis from lung adenocarcinoma with EML4-ALK rearrangement Kawamoto, Hironori Kaneko, Yugo Ryu, Kai Kuwano, Kazuyoshi BMJ Case Rep Article Thyroid metastases from lung cancer are very rare. A woman aged 42 years with a tumour in the lower lobe of the right lung was diagnosed as having lung adenocarcinoma positive for echinoderm microtubule-associated proteinlike 4-anaplastic lymphoma kinase. Positron emission tomography demonstrated fluorodeoxyglucose accumulation in the lower lobe of the right lung, the right thyroid lobe and both adrenal glands. We performed fine-needle aspiration biopsy (FNAB) and used reverse transcriptase-PCR (RT-PCR) to diagnose the patient as having metastatic lung adenocarcinoma to the thyroid gland. We believe that FNAB combined with RT-PCR can be an effective method for diagnosing metastatic lung adenocarcinoma to the thyroid gland. BMJ Publishing Group 2016-11-21 /pmc/articles/PMC5128885/ /pubmed/27872133 http://dx.doi.org/10.1136/bcr-2016-217541 Text en 2016 BMJ Publishing Group Ltd This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Kawamoto, Hironori Kaneko, Yugo Ryu, Kai Kuwano, Kazuyoshi Thyroid metastasis from lung adenocarcinoma with EML4-ALK rearrangement |
title | Thyroid metastasis from lung adenocarcinoma with EML4-ALK rearrangement |
title_full | Thyroid metastasis from lung adenocarcinoma with EML4-ALK rearrangement |
title_fullStr | Thyroid metastasis from lung adenocarcinoma with EML4-ALK rearrangement |
title_full_unstemmed | Thyroid metastasis from lung adenocarcinoma with EML4-ALK rearrangement |
title_short | Thyroid metastasis from lung adenocarcinoma with EML4-ALK rearrangement |
title_sort | thyroid metastasis from lung adenocarcinoma with eml4-alk rearrangement |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128885/ https://www.ncbi.nlm.nih.gov/pubmed/27872133 http://dx.doi.org/10.1136/bcr-2016-217541 |
work_keys_str_mv | AT kawamotohironori thyroidmetastasisfromlungadenocarcinomawitheml4alkrearrangement AT kanekoyugo thyroidmetastasisfromlungadenocarcinomawitheml4alkrearrangement AT ryukai thyroidmetastasisfromlungadenocarcinomawitheml4alkrearrangement AT kuwanokazuyoshi thyroidmetastasisfromlungadenocarcinomawitheml4alkrearrangement |