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Molecular Profiling of Circulating Tumour Cells Identifies Notch1 as a Principal Regulator in Advanced Non-Small Cell Lung Cancer

Knowledge on the molecular mechanisms underlying metastasis colonization in Non-Small Cell Lung Cancer (NSCLC) remains incomplete. A complete overview integrating driver mutations, primary tumour heterogeneity and overt metastasis lacks the dynamic contribution of disseminating metastatic cells due...

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Detalles Bibliográficos
Autores principales: Mariscal, Javier, Alonso-Nocelo, Marta, Muinelo-Romay, Laura, Barbazan, Jorge, Vieito, Maria, Abalo, Alicia, Gomez-Tato, Antonio, Maria de los Angeles, Casares de Cal, Garcia-Caballero, Tomas, Rodriguez, Carmela, Brozos, Elena, Baron, Francisco, Lopez-Lopez, Rafael, Abal, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129014/
https://www.ncbi.nlm.nih.gov/pubmed/27901069
http://dx.doi.org/10.1038/srep37820