Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/Mena(INV)-initiated invadopodium formation

The process of intravasation involving transendothelial migration is a key step in metastatic spread. How the triple cell complex composed of a macrophage, Mena over-expressing tumor cell and endothelial cell, called the tumor microenvironment of metastasis (TMEM), facilitates tumor cell transendoth...

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Detalles Bibliográficos
Autores principales: Pignatelli, Jeanine, Bravo-Cordero, Jose Javier, Roh-Johnson, Minna, Gandhi, Saumil J., Wang, Yarong, Chen, Xiaoming, Eddy, Robert J., Xue, Alice, Singer, Robert H., Hodgson, Louis, Oktay, Maja H., Condeelis, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129016/
https://www.ncbi.nlm.nih.gov/pubmed/27901093
http://dx.doi.org/10.1038/srep37874

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