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A Cascade Strategy Enables a Total Synthesis of (±)‐Morphine

Morphine has been a target for synthetic chemists since Robinson proposed its correct structure in 1925, resulting in a large number of total syntheses of morphine alkaloids. Here we report a total synthesis of (±)‐morphine that employs two key strategic cyclizations: 1) a diastereoselective light‐m...

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Detalles Bibliográficos
Autores principales:	Chu, Shuyu, Münster, Niels, Balan, Tudor, Smith, Martin D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129523/ https://www.ncbi.nlm.nih.gov/pubmed/27735107 http://dx.doi.org/10.1002/anie.201608526

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