Downregulation of EGFR in hypoxic, diffusion-limited areas of squamous cell carcinomas of the head and neck

BACKGROUND: The receptor for the epidermal growth factor (EGFR) is widely considered to be one of the central drivers of oncogenesis in squamous cell carcinomas of the head and neck region (HNSCC). Inhibition of EGFR using monoclonal antibodies is established both in the curative and the palliative...

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Detalles Bibliográficos
Autores principales: Mayer, Arnulf, Zahnreich, Sebastian, Brieger, Jürgen, Vaupel, Peter, Schmidberger, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129814/
https://www.ncbi.nlm.nih.gov/pubmed/27802455
http://dx.doi.org/10.1038/bjc.2016.336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129814/
https://www.ncbi.nlm.nih.gov/pubmed/27802455
http://dx.doi.org/10.1038/bjc.2016.336

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