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Run-on of germline apoptosis promotes gonad senescence in C. elegans
Aging (senescence) includes causal mechanisms (etiologies) of late-life disease, which remain poorly understood. According to the recently proposed hyperfunction theory, based on the older theory of antagonistic pleiotropy, senescent pathologies can arise from futile, post-reproductive run-on of pro...
Autores principales: | de la Guardia, Yila, Gilliat, Ann F., Hellberg, Josephine, Rennert, Peter, Cabreiro, Filipe, Gems, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129915/ https://www.ncbi.nlm.nih.gov/pubmed/27256978 http://dx.doi.org/10.18632/oncotarget.9681 |
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